Townhome vacation rentals in Oconee County

Find and book unique townhouse rentals on Airbnb

Top-rated townhouse rentals in Oconee County

Guests agree: these townhouse rentals are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1

Top guest favorite

Townhouse in Salem

4.96 out of 5 average rating, 53 reviews

Amenity Rich Keowee Resort - 25 min to Clemson

Enjoy the Best of Both Worlds in our spacious 4-bedroom, 3-bath townhome in the gated Keowee Key Resort. Where lake life, mountain views, and resort amenities come together for the perfect getaway. Spread over three levels with two living rooms and two sunrooms, the home offers plenty of space for families, couples, or friends traveling together. When you're visiting Lake Keowee, Clemson University, or the Blue Ridge Mountains, this home is a comfortable base for both adventure and relaxation.

Townhouse in Highlands

New! 1- Mile from Town | The Highlands Hideaway

Keep it simple at this professionally decorated, peaceful, and centrally located hideaway. This charming townhouse is nestled in the trees, sleeps 8, and is just minutes from downtown Highlands, known for its excellent local dining options, boutique shopping, and art galleries. Step outside and explore the beauty of the Blue Ridge Mountains, with Bridal Dry Falls and Veil Falls only a short drive away. You will be close to hiking trails, scenic waterfalls, and everything Highlands has to give.

Top guest favorite

The entrance of a modern resort building is framed by a striking architectural design featuring a large overhanging roof and stone accents. Steps lead up to the glass doors, while landscaped greenery complements the exterior.

Townhouse in Salem

5.0 out of 5 average rating, 80 reviews

Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom

Escape to this spacious three-story, family-friendly home w bedrooms, baths, and decks on each level—perfect for large families (sleeps 9). Pack ’n Play available, easy front-door parking, & access to resort pools, spa, and sauna included. It's a professionally cleaned, dog-friendly 3BR, 3BA townhome w loft/3 living spaces. Enjoy wooded rolling hills w wildlife, resort amenities (some activities like golf or boat rentals have fees), ping-pong, board games, and a deck fireplace under the stars.

A spacious living area is showcased, featuring comfortable seating arrangements, including a sofa and armchairs, set around a wooden coffee table. Natural light enters through glass doors leading to a balcony, and a dining area is visible in the background with a wooden table and chairs.

Townhouse in Salem

4.85 out of 5 average rating, 13 reviews

Private Balcony: Lake Keowee Home w/ Pool Access

Wooded Surroundings | Community Beach & Hiking Trails | Close to Golf Courses Peaceful lake days await at this vacation rental in Salem, South Carolina! Nestled in the picturesque Keowee Key community, this 2-bed, 1.5-bath townhome offers the ideal escape for couples and small families seeking easy access to year-round fun. Tee off at the on-site golf course, cast a line in the lake, or venture out to chase waterfalls in nearby state parks. Visiting loved ones? Clemson campus is nearby, too!

Guest favorite

A two-story townhome is shown surrounded by a spacious yard with well-maintained grass and trees. The exterior features a blend of light gray siding and brick along with two prominent windows on the ground floor. A garden area with shrubs is visible beside the entrance.

Townhouse in Seneca

5.0 out of 5 average rating, 8 reviews

Screened Patio Stay for Clemson Weekends & Lakes

3 Mi to Memorial Stadium | Step-Free Entry | Spacious Backyard Turn every Clemson home-game weekend into an easy Upstate getaway at this Seneca vacation rental, just 3 miles from campus and Memorial Stadium. After the final whistle, you can swap the crowds for cornhole in the spacious backyard, dinner on the screened patio, or a movie by the Smart TV, with Lake Keowee and Lake Hartwell nearby for an extra day of adventure. Secure your season-ready home base before the best weekends fill up!

Guest favorite

The exterior of a modern clubhouse is presented, featuring a welcoming entrance with a sloped roof and stone accents. Soft lighting enhances the landscaped path, which is lined with diverse shrubs and plants. The structure exudes a contemporary design while blending harmoniously with its surroundings.

Townhouse in Salem

5.0 out of 5 average rating, 6 reviews

The Deck House at Keowee Key Lake

Welcome to The Deck House. A 10 min. walk to Lake Keowee, a beautiful clear water lake with summer water temps in the upper 80s. Rent a boat, fish, or enjoy a sand beach for a swim. A short 10 min. drive for free access to Tennis, Pickleball, full fitness center, exercise classes and indoor and outdoor pools. Golf, boat rentals are also available for additional fees. Clemson fan? 20 mins to the football stadium. Is there more? Yes! See pictures to confirm you made the right choice!

Townhouse in Seneca

5.0 out of 5 average rating, 3 reviews

Serene Lake Keowee Condo

🌅Serene Lake Keowee Condo🌅 – Sleeps 8 | Near Downtown Seneca & Clemson Welcome to Serenity on Lake Keowee! Just minutes from downtown Seneca and Clemson University—perfect for football weekends or peaceful retreats. Highlights -Sleeps 8 -Fully equipped kitchen & open living space -Private balcony with lake views -Lake access for swimming and peaceful floating -WiFi, smart TVs, washer/dryer & free parking Location -3 min to Downtown Seneca -10 min to Clemson University

A spacious living area is furnished with comfortable gray sofas and a round coffee table, creating an inviting space. Natural light filters through large windows, illuminating a dining area with wooden chairs. A serene landscape photograph decorates the wall, enhancing the room’s calming ambiance.

Townhouse in Salem

4.71 out of 5 average rating, 14 reviews

Fun Lake Keowee TownHse Golf Tennis Picklball Pool

A lush serene setting of trees, walking paths and nature surround this 3 level townhome within the gates of Keowee Key. You will have quick access to Lake Keowee (2 marinas with kayak and boat launch and boat rentals) Pickle Ball and Tennis courts at the Fitness Center (some additional fees may apply), nearby golf and indoor and outdoor pools. This home is available as a dedicated rental property. The owners do not keep any of their personal items in the home.

Guest favorite

A large outdoor swimming pool is set against a scenic lakeside backdrop, surrounded by lounge chairs. The water glimmers in sunlight, with trees lining the perimeter. Nearby, a marina with docked boats and a parking area is visible.

Townhouse in Salem

5.0 out of 5 average rating, 12 reviews

Walk to Lake Keowee: Salem Townhome w/ Deck

Walk to Private Beach | Fireplace | Newly Renovated | 10 Mi to Clemson Escape to this 4-bedroom, 3-bath vacation rental in Salem! Perfect for families, this townhome offers ample space to unwind after exploring Lake Keowee or Table Rock State Park. With a full kitchen and access to community amenities, this townhome has everything you need for a memorable retreat! Be sure to relax by the community pool or play a round of golf before cozying up by the fireplace!

Guest favorite

Townhouse in Seneca

5.0 out of 5 average rating, 8 reviews

Boat Dock: Lake-View Retreat 5 Mi to Dtwn Clemson

Whether you're here for a relaxing lakefront getaway or to cheer on the Tigers, this impressive Seneca house is the perfect choice for you! Ideally situated on a private lot of nearly one acre on picturesque Lake Hartwell, this vacation rental boasts ample deck space, three screened porches, and a media room perfect for watching the big game. You'll love being within four miles of Clemson University, museums, parks, shops, restaurants, and more!

An overhead view of a cozy living room reveals a dark sofa and two patterned armchairs situated around a coffee table. A colorful area rug covers the hardwood floor. Natural light filters in through large windows with sheer curtains, and a television is positioned to one side next to a fireplace.

Townhouse in Salem

4.83 out of 5 average rating, 30 reviews

Keowee Key Townhome with Amenities - Pet Friendly

We are a pet friendly townhome so your puppy baby can vacation with you as well. This pristine community nestled in the foothills of the Blue Ridge Mountains surrounded by Lake Keowee features 2 marinas (plus kayaking or canoeing), 2 outdoor pools, and indoor Olympic size pool plus fitness center, on-site restaurant and the Bistro cafe. Feel free to go leisure walking on the trails throughout the compound which is all easily accessible.

A spacious living area is highlighted by comfortable seating arrangements, including leather sofas and wooden armchairs. A ceiling fan with wooden blades is present above, while natural light is allowed in through sliding glass doors leading to a patio. A round coffee table is centrally located.

Townhouse in Salem

Tall Ship 319 in Keowee Key

Tall Ship Condos are located on the north side of Keowee Key, overlooking beautiful Lake Keowee. Added benefits during your stay, include golf, dining at the Clubhouse, boat rentals at the marina, walking trails and swimming pools. We are located in such a beautiful area of SC that you will find a wealth of things to do inside the community as well as throughout the county and surrounding areas.