Villa vacation rentals in Panama City

Find and book unique villas on Airbnb

Quick stats about villa rentals in Panama City

Total vacation rentals
Explore 10 vacation rentals in Panama City
Nightly prices starting at
Panama City vacation rentals start at $130 per night before taxes and fees
Verified guest reviews
Over 430 verified reviews to help you choose
Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities
Pet-friendly vacation rentals
Find 10 rentals that welcome pets
Vacation rentals with a pool
10 properties feature pools
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Wi-Fi availability
10 of Panama City vacation rentals include wi-fi access
Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals
4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests
Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Top-rated villa rentals in Panama City

Guests agree: these villas are highly rated for location, cleanliness, and more.

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Hut in Panamá

4.71 out of 5 average rating, 7 reviews

Villa Monte Maria | Bonfire and Pool | Cerro Azul

Your mountain escape just 1 hour from Panama City. Villa Monte María is a stone cabin tucked among the pines of Cerro Azul, the closest cool-climate getaway to the capital. The shift begins before you even step out of the car: the temperature drops, the air smells of forest, and the noise of the city simply fades away. Picture your mornings wrapped in mist, with toucans and hummingbirds crossing the garden, and your afternoons measured in sunsets by your private pool. When night falls, the bon

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A welcoming private villa is surrounded by tall trees, showcasing a spacious layout. A swimming pool and trampoline are visible in the backyard, and the exterior features large windows allowing natural light. A green pathway leads to the entrance, emphasizing the serene, forested environment.

Villa in Panamá

4.73 out of 5 average rating, 26 reviews

Spacious Mountain Getaway in Paradise Cloud Forest

Private Villa located at Chagres National Park; a rainforest reserve only 30 minutes away from the airport and 50 minutes from Panama City. At 1,007 meters altitude, you will enjoy the perfect climate, bird watching, beautiful river walks, waterfalls, and many hiking trails full of wildlife, enjoy our mountain's pure air or simply relax in Nature. Bring the whole family to this great place with lots of room for fun. Bring your pets our land is completely fenced, they can run free in a vast space

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Guest favorite

An undercover terrace features comfortable seating arrangements and a swing chair, creating a relaxed environment. Light-colored flooring contrasts with dark wooden ceilings, while lush greenery is visible in the background. An outdoor kitchen area is situated at the rear, enhancing the space for social gatherings.

Villa in Panamá

4.82 out of 5 average rating, 11 reviews

Summit View Retreat- Cerro Azul Panama

Perched high in the cool mountains of Cerro Azul, Summit Guest House is a private jungle retreat with breathtaking views and abundant wildlife. Wake up to birdsong and spot toucans, hummingbirds, monkeys, and even sloths from your terrace. Relax by the pool, unwind in the hot tub, or enjoy the ever-changing mountain scenery as clouds roll through the valley. Offering spacious indoor and outdoor living, perfect for families or groups seeking both connection within easy reach of Panama City.

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Top guest favorite

A modern outdoor area features a turquoise swimming pool surrounded by lush greenery. The space includes a partially covered patio with seating options and an outdoor bar area. Tall buildings are visible in the background against a clear blue sky.

Villa in San Francisco

5 out of 5 average rating, 55 reviews

5BR House in Panama City w/ Pool & King Beds

**There is currently a construction project taking place behind the house. While most guests are not affected, there may be some daytime noise during working hours.** Beautiful home in Punta Paitilla with 5 bedrooms and 4.5 bathrooms, ideal for large groups. Enjoy a private pool, spacious living areas. Located in one of Panama City’s most exclusive neighborhoods, within walking distance to restaurants, supermarkets, shopping centers, synagogues and just minutes from the Cinta Costera.

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Guest favorite

A multi-story mansion is showcased overlooking a vibrant swimming pool, adorned with inflatable toys including a pink flamingo and a whale. Bright umbrellas provide shade over red loungers, all set against a backdrop of lush greenery and a partially cloudy sky.

Villa in Bethania

4.96 out of 5 average rating, 74 reviews

Breathtaking Views Mansion w/King Beds

Book your next thrilling Panama City vacation at our dreamy 11,500 sq. foot multi-story family mansion, superbly located on a hilltop high above the metropolis in this affluent neighborhood. Ideal for longer stays. Discover the vibrant buzz of Cinta Costera or explore the UNESCO world heritage sites at Casco Viejo – all under 5 km away from your doorstep. Enjoy a refreshing dip into the swimming pool and admire the sublime views of the Panama City Skyline from our unique roof terrace.

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Top guest favorite

The private outdoor pool is set against a backdrop of lush greenery and the home's elegant architecture. Comfortable seating arrangements are positioned nearby on the pool deck, inviting relaxation. Large windows reflect natural light, enhancing the spaciousness of the surrounding area.

Villa in San Francisco

4.98 out of 5 average rating, 118 reviews

Beautiful House in Panama w/ King Beds + Pool

Beautiful home in Punta Paitilla featuring 6 bedrooms, 5.5 bathrooms, and 8 beds, comfortably accommodating up to 16 guests. Enjoy a private pool, in-home gym, and spacious, modern living areas designed for families, groups, or business travelers. The layout offers both privacy and comfort across two levels. Located in one of Panama City’s most exclusive neighborhoods, just minutes from restaurants, shopping centers, supermarkets, and the Cinta Costera.

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A spacious living area features a combination of white sofas and vibrant seating, surrounded by large windows that allow natural light. Colorful pillows and a patterned rug add visual interest. A wooden staircase leads to the dining space that is visible in the background.

Villa in Panama

4 out of 5 average rating, 7 reviews

La Semilla | Jungle Mansion | Panama City

Just one hour from Panama City, you will find La Semilla | Jungle Mansion in the Cerro Azul cloud forest, bordering the Chagres National Park. La Semilla is a perfect private escape to relax or party in serene privacy. Boasting 7 luxurious king bedrooms suites all with A/C, flatscreens, wi-fi, en suite bathrooms and memory-foam mattresses. Amenities: bar, chef/restaurant, jacuzzi, billiards, movie lounge, and pool.

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A two-story structure displays a soft pink exterior with large glass windows. Lush green landscaping surrounds the entrance, while a driveway leads to a carport featuring a parked vehicle. The property offers unobstructed views of the nearby golf course, enhancing the sense of tranquility.

Villa in Panamá

Agradable villa de Playa Villas Decameron Rio Hato

En este alojamiento se respira tranquilidad: ¡relájate con toda la familia, excelente vista al campo de Golf acceso al club de playa privado contamos con seguridad las 24 horas, lugar tranquilo para relajarse y pasarla bien en familia.

The villa is surrounded by greenery, featuring a two-story structure with distinctive architectural elements. A well-maintained lawn extends in front of the house, while a stone pathway leads to the entrance. Various plants and trees provide a natural setting.

Villa in Panamá

4 out of 5 average rating, 6 reviews

Tranquilidad y paz conecta con la Naturaleza 🌤

Descansa en nuestra villa familiar conecta con todo los paisajes dentro de esta propiedad que es parte del Parque Nacional Chagres en nuestra villa te sentiras como en casa a pocos minutod de la ciudad.

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