Aparthotel vacation rentals in Panama

Find and book unique aparthotel rentals on Airbnb

Top-rated aparthotel rentals in Panama

Guests agree: these aparthotel rentals are highly rated for location, cleanliness, and more.

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Standard room with terrace and panoramic city view

Enjoy a comfortable stay in this standard room for 2 people in an aparthotel located in the heart of the Old Town of Panama City. With 20 m² of spacious and bright space, it is ideal for couples or travellers looking for an excellent location and all the amenities. Surrounded by restaurants, cafeterias and the main tourist spots such as Tomás Herrera Park, Independence Square and the Interoceanic Canal Museum, this accommodation offers easy access to the metro, buses and airports.

A living area featuring two distinct chairs in red and blue upholstery. A sleek television is mounted on the wall, while a round side table sits in front. Natural light filters through sheer curtains, enhancing the contemporary design.

Hotel room in San Felipe

Majestuosa Suite en Panama

Discover the comfort of this elegant 40 m² Deluxe Suite, perfect for 2 people, located in the heart of the Old Town of Panama City. Ideal for those seeking spaciousness, style, and an excellent location. Enjoy a lively environment, surrounded by restaurants, cafés and the main tourist attractions such as the Canal Museum, Independence Square and the Presidential Palace. Includes: wifi, air conditioning, Tv, hairdryer, spa, private balcony and kitchen with coffee maker.

Superhost

Hotel room in Bella Vista

4.7 out of 5 average rating, 10 reviews

The Urban Loft #203 | La Résidence Panamá

Contemporary comfort for the modern traveler. This 69-71 m² suite includes 2 bedrooms (two king beds - bedroom open in pb+ one sofabed), 2 bathrooms, full kitchen, washer/dryer, coffee machine, and A/C — everything you need to feel at home. At LA RÉSIDENCE, we offer more than just a stay — we deliver a complete experience. With a blend of modern design, central location, and thoughtful amenities, we create a space built for your comfort and productivity.

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Hotel room in San Felipe

Habitacion para 4 huespedes en inmejorable Zona Pa

Spacious and bright Twin Suite of 40 m² with capacity for 4 people, ideal for families or groups of friends. Located in the heart of the Old Town of Panama City, steps away from historic squares, museums, cafes, and restaurants. Modern accommodation, fully equipped with wifi, air conditioning, Tv, hairdryer, spa access and kitchen with coffee maker. Perfect for a comfortable stay in one of the most vibrant areas of the city.

Superhost

A welcoming exterior view of Serenade Lodging Rooms features a prominent sign amidst lush greenery and a well-maintained entrance. Stone accents enhance the modern façade, and a pathway leads to the building, providing easy access for guests.

Hotel room in San Francisco

4.81 out of 5 average rating, 32 reviews

Serenade Lodging Rooms

Si necesitas un lugar donde te quieras sentir en casa fuera de tu casa, Serenade Lodging Rooms te lo ofrece.Habitaciones súper cómodas,con su cocineta incluida ... todo con los mejores estándares.. Desayuno completo incluido.. delicioso y variado.. y una excelente atención pues en Serenade Lodging Rooms usted es nuestra prioridad.

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A bright living area features a round glass dining table with four black chairs. A red couch is positioned against the wall, while a kitchenette is equipped with a stove, refrigerator, and various appliances. A wall-mounted television is visible, along with light-colored walls and tiled flooring.

Hotel room in El Cangrejo

4.82 out of 5 average rating, 11 reviews

COMODO APARTAMENTO EN EL CANGREJO

Apartamentos privados completamente amoblados para 2 personas, de 30m2 con 1 habitación, cocina, baño privado, sala-comedor. El área de balcón es comunal. Incluye aire acondicionado y agua caliente. Ubicado en el centro de la ciudad, cerca de restaurantes, farmacias, mini-mercados, karaokes, entre otros servicios.

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A small balcony features a round, white, metal table and two matching chairs. A newspaper is spread open on the table next to a cup of coffee and a colorful pastry. The balcony overlooks a charming street, with bright light filtering through the lush plants.

Hotel room in San Felipe

Deluxe Suite in the Heart of Panama City

Enjoy an exclusive stay in our 30 m² Deluxe Suite, a modern, comfortable accommodation filled with natural light, ideal for two people. Located in the heart of Panama City's historic district, this apart-hotel places you steps away from the main tourist, cultural, and gastronomic attractions.

A tranquil pool area is featured, accented by decorative planters and a round float resting on the water's surface. A light-colored building can be seen in the background, complemented by lush green trees. A vehicle is parked nearby, adding to the convenience of the setting.

Hotel room in Mariato

Cativa House

Disfruta con toda la familia y amigos con nuestras amplias habitaciones en Mariato, contamos con piscina, area de barbacoa y nuestra ubicación es cerca de comercios de la localidad. A 5 minutos de Playa Reina y también cerca de playa torio, playa escondida y otras.

A welcoming entrance opens to a cozy room, framed by lush green plants. The double doors feature intricate designs, allowing glimpses of a blue bed inside. The tiled pathway leads to a stone bench, enhancing the inviting ambiance of the space.

Hotel room

Olas del Oeste (Waves of the West)

Right in the charming center of San Carlos and next to the park. Enjoy easy access to popular shops and restaurants, a grocery store, bakery and coffeehouse all surrounding the inn. Ten minute walk to the amazing San Carlos beach and great for surfers!