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Places to stay near Plaza de Santo Domingo

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Top-rated vacation rentals near Plaza de Santo Domingo

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Villa in Centro
4.86 out of 5 average rating, 162 reviews

Amazing House +2 Pools + Rooftop | Historic Center

We are a luxury boutique house located in the heart of the city nearto best restaurants and plazas. . With 5 rooms spread over 3 floors and rented as a complete house with a maximum capacity of 12 people. Within the value per night is included breakfast, 1 cook, 1 housekeeper, 1 maintenance staff and a concierge who will be in charge of the house services and available to cook lunches, dinners or others (ingredients must be provided by the guests). Fast WIFI speed at the house for home office.

Guest favorite
A serene outdoor patio features a private pool surrounded by lush greenery. Comfortable seating areas with woven chairs are positioned nearby, illuminated by soft lighting. The pool has gentle water features, enhancing the tranquil environment of the space.
Apartment in Centro
4.89 out of 5 average rating, 174 reviews

Santos de Piedra Apartment in the walled City

Luxurious PRIVATE colonial apartment, with the best location, in front of the Cathedral of Santa Catalina. First level: living-dining room with an open-plan kitchen laundry area and social bathroom. Bedroom with private bathroom and king-sized bed, also patio with a pool for private use. Second floor: two bedrooms with private bathrooms, one with Queen bed and the other with twin beds Free housekeeper / breakfast and lunch negotiable with Sonia / free coffee / free water Rossana and Martin

Guest favorite
An airy living space features a light-colored sofa with decorative cushions, a coffee table, and a dining area with a circular table and chairs. Large windows allow natural light to fill the room, while a ceiling fan and a chandelier provide comfort. A hammock can be seen strung between two walls.
Apartment in Centro
4.9 out of 5 average rating, 119 reviews

Chic Colonial Retreat – Walk Everywhere

Welcome to my cozy colonial apartment in Cartagena’s Old Town, just steps from Santo Domingo Square. This is my home, and I’ll make sure everything is clean and ready for your stay. Perfect for couples or solo travelers, the apartment includes: ❄️ Two air conditioning units for your comfort 👩‍🍳 Fully equipped kitchen 🚿 Hot water. 🛏️ Comfy double bed 🌿 Spacious colonial balcony 🔐 Digital self check-in 👮‍♂️ Security staff on duty 24/7 🚫 No visitors allowed (per building rules)

Top guest favorite
A rooftop terrace features a relaxing hot tub surrounded by lush greenery. Comfortable seating areas include wicker chairs and a wooden table, with stunning views of the city skyline and distant hills under a clear blue sky.
Home in Getsemany
4.99 out of 5 average rating, 126 reviews

Casa O Getsemani Lux Boutique House

Welcome to Casa O Getsemani! Immerse yourself in luxury at this new 4-story haven in in the coolest neighborhoods.Designed by the renowned architect Vladimir Caballero, our house accommodates 6 guests with utmost comfort. Enjoy complimentary one airport transport, delicious breakfast, and attentive housekeepers. Elevate your stay with optional catering, entertainment, and exciting tours. Your unforgettable getaway awaits! Book now and create beautiful memories at Casa O Getsemani.

Top guest favorite
A serene pool area is surrounded by tropical greenery, featuring a circular plant island at the center. Plush seating is available beside the pool, with draped curtains providing a sense of privacy. Soft lighting highlights the textured walls, creating a calming ambiance.
Home in Centro
4.91 out of 5 average rating, 231 reviews

Private Heated Pool+Jacuzzi | Colonial Walled City

Step into one of Cartagena's most iconic streets — Calle de las Damas — and into a beautifully appointed colonial home that blends centuries of history with every modern comfort. Located in the heart of the Walled City, Casa Calle de las Damas is the perfect base for experiencing the real magic of Cartagena. Whether you're traveling with family or a group of friends, this spacious 2-bedroom, 2 1/2-bathroom home offers an elegant and relaxed atmosphere you'll never want to leave.

Top guest favorite
A spacious loft suite is presented with an open layout, featuring a modern spiral staircase leading to a lofted sleeping area. Soft neutral tones and green plant decor enhance the environment. Seating arrangements include a large, curvy couch and a wooden table, creating a comfortable gathering space.
Apartment in Centro
5.0 out of 5 average rating, 102 reviews

Luxury Suite/Loft Apt/CityCenter

1 BR Loft Suite in the heart of Cartagena inspired by some of the finest 5 star Hotels in the world. Located inside the walls of the old city, within walking distance to shops, entertainment, restaurants, nightclubs & bars. Enjoy staying in this Unesco Heritage town full of history & excitement. Fully equipped kitchen with Washer/Dryer, Queen Sized Bed, TV, Netflix and 400MbWi-Fi. Our modern beach vibe apartment is perfect for a couple to enjoy and relax Insta @pombocartagena

Guest favorite
Apartment in Centro
4.96 out of 5 average rating, 457 reviews

Boutique Stay in Historic Center + Local Concierge

Stay in the heart of Cartagena with a curated local experience. Your stay includes access to a private concierge who can help design your trip—from hidden restaurants to unforgettable moments. Recently redecorated 2-bedroom apartment with full A/C, a bright and relaxed atmosphere, Smart TV, PS4, dining for six, and 24/7 security. Steps from vibrant plazas, cafés, and historic landmarks—your Caribbean retreat awaits.

Guest favorite
A rooftop terrace is presented with a spiral staircase, leading to additional levels. A private pool is featured along one side, complemented by lounge chairs and a sofa. Soft lighting highlights the terracotta walls, enhancing the evening ambiance.
Home in Centro
4.88 out of 5 average rating, 155 reviews

casa encantada

Walled city. Magnificent four-story house exclusively for guests. With a small private pool in the Rooftop. Located in the historic center of the walled city of Cartagena near the Baruco restaurant, bars, galleries, house of the inquisition, Plaza Botero, clock tower, shops, pharmacies, art with a spectacular viewpoint. With air conditioning in the living room, kitchen and bedrooms.

Guest favorite
A spacious living area is characterized by high ceilings with wooden beams and a large chandelier. Comfortable seating is provided with two armchairs and a sofa. A wooden table with an artistic design sits in the center, complemented by a bar area in the background.
Apartment in Centro
4.88 out of 5 average rating, 669 reviews

Casa del Colegio

A charming two bedroom, 2.5 bathroom apartment in the center of the Old Town, a few steps from Cartagena’s coveted museums, restaurants, galleries and shops. The property includes a large living room, dining area, kitchen, and balcony overlooking picturesque colonial streets. Housekeeping is included (every other day) to ensure a stress-free stay (except Sundays & holidays).

Top guest favorite
A rooftop terrace features a relaxing Jacuzzi surrounded by lounge chairs, with vibrant greenery nearby. The scene is enhanced by a stunning sunset and a historic tower in the background, creating a serene atmosphere for relaxation.
Apartment in Centro
4.98 out of 5 average rating, 224 reviews

Exclusive Apt in Walled City | Rooftop Jacuzzi!

Welcome to this EXCLUSIVE apartment right in the heart of the Walled city. Just steps away from restaurants, bars, coffee shops and some of the most iconic plazas, churches and museums. Perfect for weekend getaways, business trips, working nomads or cozy home base while exploring everything Cartagena has to offer! NO UNREGISTERED VISITORS ALLOWED!

Guest favorite
A spacious living area is presented, featuring a comfortable sofa adorned with patterned cushions. A wooden coffee table sits in front, with a decorative plant nearby. The loft's upper level is visible, offering a glimpse of the bedroom, while soft lighting enhances the inviting ambiance.
Loft in Centro
4.84 out of 5 average rating, 204 reviews

Classic loft in the heart of the Walled City

Enjoy an unforgettable experience within Cartagena's walls. This loft is located in one of the city's most iconic buildings and historical heritage, within walking distance of the best restaurants, cafes, tourist sites, recreation and entertainment. Come and learn a little about our history and rest in a clean place with the comforts of home.

Guest favorite
A refreshing pool is situated on a terrace, surrounded by lush greenery. Two glasses sit on a wooden tray alongside neatly arranged towels. The background features an expansive ocean view and the skyline of a nearby city under a partly cloudy sky.
Villa in Centro
4.89 out of 5 average rating, 132 reviews

Historic oceanfront villa/private rooftop pool

A private oasis nestled on Cartagena’s iconic city walls. Casa de la Artillería blends timeless colonial charm with modern comfort, featuring a private rooftop pool, breathtaking Caribbean views and an unbeatable location just steps from the city’s finest restaurants, cafés and vibrant plazas.

Popular amenities for vacation rentals near Plaza de Santo Domingo