
Places to stay near Plaza de Santo Domingo
Book unique vacation rentals, homes, and more on Airbnb
Top-rated vacation rentals near Plaza de Santo Domingo
Guests agree: these stays are highly rated for location, cleanliness, and more.

Amazing House +2 Pools + Rooftop | Historic Center
We are a luxury boutique house located in the heart of the city nearto best restaurants and plazas. . With 5 rooms spread over 3 floors and rented as a complete house with a maximum capacity of 12 people. Within the value per night is included breakfast, 1 cook, 1 housekeeper, 1 maintenance staff and a concierge who will be in charge of the house services and available to cook lunches, dinners or others (ingredients must be provided by the guests). Fast WIFI speed at the house for home office.

Santos de Piedra Apartment in the walled City
Luxurious PRIVATE colonial apartment, with the best location, in front of the Cathedral of Santa Catalina. First level: living-dining room with an open-plan kitchen laundry area and social bathroom. Bedroom with private bathroom and king-sized bed, also patio with a pool for private use. Second floor: two bedrooms with private bathrooms, one with Queen bed and the other with twin beds Free housekeeper / breakfast and lunch negotiable with Sonia / free coffee / free water Rossana and Martin

1 BR Luxury Suite/Loft Historic Center
1 BR Loft Suite in the heart of Cartagena inspired by some of the finest 5 star Hotels in the world. Located inside the walls of the old city, within walking distance to shops, entertainment, restaurants, nightclubs and bars. Enjoy staying in this Unesco Heritage town full of history and excitement. Fully equipped kitchen with Washer/Dryer, King Sized Bed, pullout Queen Size Couch, Television, Netflix & 300MbWi-Fi. Our modern beach vibe apartment is perfect for a couple to enjoy and relax.

Chic Colonial Retreat – Walk Everywhere
Welcome to my cozy colonial apartment in Cartagena’s Old Town, just steps from Santo Domingo Square. This is my home, and I’ll make sure everything is clean and ready for your stay. Perfect for couples or solo travelers, the apartment includes: ❄️ Two air conditioning units for your comfort 👩🍳 Fully equipped kitchen 🚿 Hot water. 🛏️ Comfy double bed 🌿 Spacious colonial balcony 🔐 Digital self check-in 👮♂️ Security staff on duty 24/7 🚫 No visitors allowed (per building rules)

Casa O Getsemani Luxury Boutique House
Welcome to Casa O Getsemani! Immerse yourself in luxury at this new 4-story haven in in the coolest neighborhoods.Designed by the renowned architect Vladimir Caballero, our house accommodates 6 guests with utmost comfort. Enjoy complimentary one airport transport, delicious breakfast, and attentive housekeepers. Elevate your stay with optional catering, entertainment, and exciting tours. Your unforgettable getaway awaits! Book now and create beautiful memories at Casa O Getsemani.

Private Heated Pool+Jacuzzi | Colonial Walled City
Step into one of Cartagena's most iconic streets — Calle de las Damas — and into a beautifully appointed colonial home that blends centuries of history with every modern comfort. Located in the heart of the Walled City, Casa Calle de las Damas is the perfect base for experiencing the real magic of Cartagena. Whether you're traveling with family or a group of friends, this spacious 2-bedroom, 2 1/2-bathroom home offers an elegant and relaxed atmosphere you'll never want to leave.

Boutique Stay in Historic Center + Local Concierge
Stay in the heart of Cartagena with a curated local experience. Your stay includes access to a private concierge who can help design your trip—from hidden restaurants to unforgettable moments. Recently redecorated 2-bedroom apartment with full A/C, a bright and relaxed atmosphere, Smart TV, PS4, dining for six, and 24/7 security. Steps from vibrant plazas, cafés, and historic landmarks—your Caribbean retreat awaits.

casa encantada
Ciudad amurallada Magnifica casa de cuatro niveles exclusivos para los huéspedes. Con una pequeña piscina privada en la Azotea. Ubicada en el centro histórico de la ciudad amurallada de Cartagena cerca del restaurante Baruco, bares, galerías, casa de la inquisición, plaza botero, torre del reloj, tiendas, farmacias, arte con un mirador espectacular. Con aire acondicionado en sala, cocina y habitaciones.

School House
A charming two bedroom, 2.5 bathroom apartment in the center of the Old Town, a few steps from Cartagena’s coveted museums, restaurants, galleries and shops. The property includes a large living room, dining area, kitchen, and balcony overlooking picturesque colonial streets. Housekeeping is included (every other day) to ensure a stress-free stay (except Sundays & holidays).

Facing the Caribbean Sea. Apartment on the wall
Fantastic fully equipped apartment: -High-speed WiFi. 400 Mbps - Views over the Caribbean Sea from our spectacular private terrace. Dreamy sunsets. - 3 bedrooms with air conditioning in each of them. - Air conditioning in common areas. - 4 Bathrooms - Fully-equipped kitchen. - 24-hour security - 24-hour check-in - Sleeps 6 -Workspace (desk and chair)

Exclusive Apt in Walled City | Rooftop Jacuzzi!
Welcome to this EXCLUSIVE apartment right in the heart of the Walled city. Just steps away from restaurants, bars, coffee shops and some of the most iconic plazas, churches and museums. Perfect for weekend getaways, business trips, working nomads or cozy home base while exploring everything Cartagena has to offer! NO UNREGISTERED VISITORS ALLOWED!

Historic oceanfront villa/private rooftop pool
A private oasis nestled on Cartagena’s iconic city walls. Casa de la Artillería blends timeless colonial charm with modern comfort, featuring a private rooftop pool, breathtaking Caribbean views and an unbeatable location just steps from the city’s finest restaurants, cafés and vibrant plazas.
Popular amenities for vacation rentals near Plaza de Santo Domingo
Condo rentals with wifi

Inside the Walls · Rooftop Jacuzzi · Pool

Exclusive Oasis in Cartagena’s. Old City

Exclusive Condo H2 / Hyatt 2 BD Bayview

Charming flat inside walledcity 303

House with an unparalleled location and views in Centro

Charming pool apartment in Historical Getsemani

Luxury 2-BR apt inside the old city

BOHO l Apartment | Cartagena Walled City
Family-friendly house rentals

El Porton de San Antonio, Historic Center!

Casa Coco • Private Villa • Pool & Rooftop Jacuzzi

Getsemani/Luxury house/Private pool/Casa Stephanie

Casa Flamingo | Private Pool in Walled City

Stunning Villa w/private terrace & splash pool

Casa San Juan (Gethsemani)

Casa Rosa - Private Pool and Jacuzzi

Beautiful 2BR 5 minutes from Downtown - Casa Vert
Apartment rentals with air conditioning

Charming apt in the Heart of Old Town with Balcony

*Ocean*View*Luxury*2kingBeds/2bath w Ac*Near Beach

best location in historic center+charming oasis

Stay on Calle de las Carretas

Stunning view. Amazing location.

Unbeatable location 1 ROOM Magic Apt

Panoramic Romantic Apartment

HISTORICAL CENTER!!! THE BEST LOCATION
Other great vacation rentals near Plaza de Santo Domingo

Mangostino Loft - Historic Center

Charming Oasis with Pool in Walled City

Modern 3BR/2BA Gem in Cartagena

Classic loft in the heart of the Walled City

Beautiful Designer Loft in the Old City

Restored Treasure | Luxury in the Walled City
Villa de Tovar - Walled City

Cozy & Modern loft in Historical City Center
Destinations to explore
- Bocagrande
- Morros City Apartamentos
- Walls of Cartagena
- Playas de Bocagrande
- Edificio morros Eco
- Playa Blanca
- Plaza Bocagrande
- Torre Del Reloj
- Cholón (Islas del Rosario)
- Santa Cruz del Islote
- Karibana Cartagena
- Morros Vitri Building
- Aviario Nacional De Colombia
- Centro de Convenciones Cartagena de Indias
- Las Bovedas
- La Serrezuela
- Parque Plaza Fernández Madrid
- Cafe del Mar
- Múcura Hotel & Spa
- Historical Museum of Cartagena de Indias
- Museo Naval del Caribe
- Muelle La Bodeguita
- Convent of Nuestra Señora de la Candelaria de la Popa
- Old Boots
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes





