
Guesthouse vacation rentals in Santo Domingo
Find and book unique guesthouse rentals on Airbnb
Quick stats about guesthouse rentals in Santo Domingo

Total vacation rentals
Explore 70 vacation rentals in Santo Domingo

Nightly prices starting at
Santo Domingo vacation rentals start at $10 per night before taxes and fees

Verified guest reviews
Over 1,710 verified reviews to help you choose

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
70 of Santo Domingo vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santo Domingo rentals
Top-rated guesthouse rentals in Santo Domingo
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Private Cozy Apartment Studio
One bedroom studio, centrally located in the heart of El Millón, Santo Domingo, where comfort, convenience, and warm space offers the intimate feel of a family home, featuring: A private entrance for your complete privacy. Dedicated parking for your convenience and peace of mind. Whether you're visiting for leisure or business, our studio is thoughtfully designed to meet your needs. Remote workers will appreciate the high-speed internet, ensuring uninterrupted connectivity throughout your stay.
LocationValueCleanliness

Centric & Elegant Studio/Colonial Style/Ample Yard
Unique studio within a renovated property. Large patio with fence and electric gate. Ideally located, 2 miles away from the Colonial Zone, 3 from Downtown. Hospital, Laundry, Sea View within 2 blocks. Supermarket, restaurants, museums within 1 mile. Less than 0.5 miles away from 2 subway stations. Fast Wifi (100+ Mbps). Smart speaker can control lights, AC, adjust temperature or play your favorite music. 4K TV w/swivel base, includes YouTube, Netflix, PrimeVideo, Disney and Star+. Queen bed.
ValueFamilyAccess

Giuliela Boutique Stay – Entire Residence
A private sanctuary where history meets intention. This exclusive stay includes both Luna and Sole Suites within GIULIELA, a beautifully restored 1930s residence in Gazcue. While guests enjoy their own private accommodations, my family and I reside in the main house, allowing us to offer personalized local recommendations, and attentive hospitality. Curated design, timeless charm, and a touch of quiet luxury create an intimate experience that blends authentic local living with refined comfort.

VillaMella Oasis 2bedroom2bathroom Patio Hot Water
Welcome to your Oasis in Villa Mella. Relax in comfort and luxury with a second-floor-level, 2 queen beds, 2 private baths, and a fold-out sofa. Enjoy A/C, hot water, fast WIFI, and 3 Roku TVs with Netflix. Secure smart lock entry and 24/7 on-site staff that will ensure peace of mind. Just a 5-minute walk from the Gregorio Gilbert Metro station. Bring the whole family to this great place with lots of room for fun. Need a driver? We've got you covered. Let us melt your stress away! Book now!
ValueLocationBathroom

Cozy 2 BR with BBQ
This 2 bedroom apartment with BBQ private area is truly bright and cozy . It takes 25 minutes to arrive from the airport. The spacious master bedroom has a queen size bed and the very bright single room have two twins bed. You have discount with our car rental services with airport pick-up. The neighborhood is very safe, is private with access control and very clean, there are many restaurants nearby many bars, gyms, movie theaters, shopping malls . The neighbours are lovely and quiet.
FamilyLocationIndoor spaces

Nido del patio, 40 min to Bocachica beach 5 center
You will have the entire apartment just for you. Enjoy the tranquility that the area offers, an ideal place to rest and work, and a strategic point to travel to places of interest You are responsible for cleaning the accommodation during your stay. It is delivered clean. If you need it, you can request cleaning service at an additional charge. The patio is rarely shared. Usually, only you will enjoy the patio. The host is in charge of cleaning the patio area.
ValueLocationBackyard

Cozy apartment for work / holidays.
Comfortable apartment, on second level, with private parking, ideal for holiday trips, congresses, jobs and others. Close to shopping centers, Recreational park, clinics, universities; 25 minutes from the colonial area. Located in downtown area of the city, in the urbanization El Millón del Distrito Nacional. Peaceful, residential place with access to the main roads of the city.
ValueLocationAmenities

Guest House in the city/pool/USA Embassy
You no longer need to leave the city to feel in the mountains, this is an independent 1 bed 1 bath Guest House in a closed residence with a 10-meter pool shared with the Hosts. With a Coway potable water filter. Supermarkets, Cinema, Shops, and Hair Salon nearby. A few minutes from the center of Santo Domingo and 1.8 km from the American Embassy.
FamilyLocationHospitality

Tú rinconcito de paz en SDO
Kick back and relax in this calm, stylish space. “Tu rinconcito de Paz” is an oasis in the middle of the city rush, take some fresh air in our outdoor Gazebo area, enjoy the privacy and security of our small but cozy house. Commercial centers as Carrefour and numerous restaurants are located at 8 minutes away from our spot.
LocationNearbyHospitality

Cozy Separate Room in Santo Domingo Colonial
Book – Private Studio with Shared Patio. Comfortable - spacious, close to colonial zone, presidential palace, independence park, Malecon. First city in the American continent. Most touristic area of Santo Domingo. Most tourist area of Santo Domingo! Great for sightseeing
LocationValueTV

Private oasis with pool in a quiet residential area
Private pool just for you. Independent attached house with large garden and terrace ideal to enjoy as a family. Located in a quiet and safe residential area, close to everything. Air-conditioned and comfortable spaces. Perfect for getaways, weekends and a break in the city.
ValueFamilyComfort

Villas Na’ Keys
Discover a unique retreat where comfort, privacy, and beauty come together to offer an unforgettable experience. Our villa has been carefully designed to provide a cozy and elegant atmosphere, ideal for both relaxing getaways and special moments with family and friends.
LocationHospitality
Popular amenities for Santo Domingo guesthouse rentals
Family-friendly guest house rentals

Villas Ureña,

Vintage-Modern 2floor GuestHouse

Private apartment

Cozy, quiet, safe
LocationValueLaundry

save your pocket
ValueComfortHospitality

Stay at Pepa's
LocationIndoor spacesComfort

3 Private Room El Vergel
ValueLocationSleep quality

Wi-Fi, TV, toilet, air conditioning, refrigerator, no. 3 and 4
LocationValueQuiet
Guest house rentals with a patio

Relax in this cozy villa
FamilyValueAccuracy

The best option
ValueLocationAir conditioning

Double suite room in Aut Las Américas

Hermosa villa Familiar, villa palmera Guerra

Charming Shelter - Suite #5
FamilyLocationOutdoor spaces

Our Home Zudelyn H3

6 Guest Art House

Beautiful room in the Colonial area
ValueLocationBathroom
Guest house rentals with a washer and dryer

The best option to rest near the city

Villa el paraíso, Guerra
FamilyPoolComfort

Brisa Oriental

guest house
Hospitality

Casa en Villa Marina, Los Ríos de Santo Domingo
AccuracyHospitality

Secure★DCGen★Full Kitchen★100+Mbs★Comfy Bed★W/D
LocationFamilyAmenities

Guestroom Deluxe in Santo Domingo

ZONA Colonial Walking distance B
LocationValueAir conditioning
When is the best time to visit Santo Domingo?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $26 | $27 | $24 | $26 | $26 | $22 | $26 | $29 | $35 | $29 | $28 | $27 |
| Avg. temp | 78°F | 78°F | 79°F | 80°F | 81°F | 82°F | 83°F | 83°F | 83°F | 82°F | 81°F | 79°F |
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- Playa Nueva Romana
- Ciudad Juan Bosch
- Malecón
- Metro Country Club
- Playa Guayacanes
- Blue Mall
- Playa Hemingway
- Downtown Center
- Megacentro
- Agora Mall
- Zona Colonial
- Teatro Nacional Eduardo Brito
- Bella Vista Mall
- Galería 360
- Dr. Rafael Ma. Moscoso National Botanical Garden
- Parque Iberoamerica
- Cathedral of Santa María la Menor
- Columbus Park
- The 3 Eyes National Park
- Columbus Lighthouse
- Casa De Teatro
- Playa Caribe
- Independence Park
- Kahkow Experience
- Things to do Santo Domingo
- Nature and outdoors Santo Domingo
- Food and drink Santo Domingo
- Things to do Distrito Nacional
- Nature and outdoors Distrito Nacional
- Art and culture Distrito Nacional
- Food and drink Distrito Nacional
- Things to do Dominican Republic
- Tours Dominican Republic
- Nature and outdoors Dominican Republic
- Sightseeing Dominican Republic
- Food and drink Dominican Republic
- Entertainment Dominican Republic
- Sports activities Dominican Republic
- Art and culture Dominican Republic
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
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- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes







