House vacation rentals in Santo Domingo

4.99 out of 5 average rating, 145 reviews

A spacious living area features a light-colored sofa adorned with decorative pillows. A coffee table with floral arrangements complements two blue accent chairs nearby. Large windows allow natural light to fill the room, enhancing the bright, airy atmosphere.

Home in Los Prados

Casa Serena: cozy, modern, spacious and peaceful

Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

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A welcoming living area features a comfortable wooden sofa adorned with green cushions, accompanied by two wooden chairs. A round wooden coffee table is centered on a patterned blue and white rug, while a potted plant adds a touch of greenery near a window.

4.86 out of 5 average rating, 155 reviews

New - 3 Bd House Zona Colonial + Private Rooftop

🌴🥥 Welcome to the perfect oasis in the Dominican Republic. We are so happy to host you ! We are centrally located in La Zona Colonial, the historic central neighborhood of the Dominican Republic's capital, Santo Domingo. It is the oldest continuously inhabited European-established settlement in the Americas. We are steps away from restaurants, night life, bars, museums and landmarks. Casa Altagracia is an eclectic, unique and curated house welcoming families, couples and friends.

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5 out of 5 average rating, 8 reviews

Modern apartment in the Colonial Zone

Exclusive apartment in the Colonial Zone of Santo Domingo, ideal for those seeking history, comfort, and a unique experience. Located in one of the city's most iconic areas, this elegant space combines colonial charm with modern amenities. It has one bedroom, a large and bright living room, and a fully equipped kitchen. Its main attraction is a spectacular private terrace with a Jacuzzi (room-temperature water), perfect for relaxing and enjoying the Caribbean climate.

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A bright and airy entrance leads to a serene outdoor area with a pool. The space is framed by modern glass walls, showcasing inviting seating and greenery. Natural light filters through, enhancing the layout that connects indoor and outdoor living.

5 out of 5 average rating, 60 reviews

Stunning villa in Zona Colonial

Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

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4.95 out of 5 average rating, 170 reviews

The living area features a light blue sofa paired with a small neutral-toned coffee table. A colorful piece of wall art hangs above the sofa, and a dining table is visible in the corner. A ceiling fan and green curtains enhance the space, while natural light enters from a nearby window.

Home in Santo Domingo

Cozy, central and well-equipped place

We are located in a central and quiet part of the city, with access to 27 de Febrero, Máximo Gómez, and Jhon F. Kennedy avenues. Nearby are the Ibero-American University (Uníbe), Zambil shopping center, Banco Popular Dominicano Tower, as well as pharmacies and health centers. The apartment is located on the first floor, with independent access, parking, and an electric gate. It has a cable system, high-speed WiFi, and an inverter.

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5 out of 5 average rating, 12 reviews

Casa Aurelia + Pool + Sleeps 4

Set in the heart of the Zona Colonial, this beautifully restored 17th-century home blends authentic colonial architecture with a fresh, modern feel. Domus Santa Bárbara features five thoughtfully designed apartments surrounding a stunning pool, reserved exclusively for our guests. Enjoy an unforgettable stay in a space where heritage meets modern living—ideal for relaxing, unwinding, and creating memorable moments together.

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A covered terrace features a wooden floor, surrounded by potted plants. Four chairs with colorful cushions face a wooden table. A hammock and a cozy blue chair are positioned nearby, with an open view of the rooftops in the background.

4.96 out of 5 average rating, 115 reviews

Charming Old City Corner House

This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

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Superhost

An inviting entrance features a pair of wooden doors, framed by a rustic archway and accented by a central chandelier. Warm terracotta tiles reflect natural light, guiding visitors toward the inner living spaces, while artwork enhances the walls along the corridor.

4.82 out of 5 average rating, 108 reviews

Your 2BR House + Terrace in the Colonial Zone

Feel the history in this authentic Colonial house from the XVI century with all the modern amenities you will need to make your trip unforgettable. Enjoy a walk to history in the oldest city of America. Visit impressive cultural sites, exquisite restaurants and bars. Have fun in a great night atmosphere. In just minutes you can be in the ocean shore ( malecon ) or in the Colonial promenade.

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A two-story building is depicted, featuring a light-colored exterior and a pop of blue accents. The lower level includes a planter box and secured entrances. A person rides a bicycle nearby, adding a sense of activity to the quiet street setting adorned with plants.

4.88 out of 5 average rating, 336 reviews

Heart of the colonial zone, Billini 54

At the very heart of the most exclusive part of the colonial city where all the fun and interesting activities take place. This beautiful one-bedroom apartment is on the first floor of a small building next to the colonial gate 4D cinema, electric bike rentals, beer market, food markets, historical landmarks, exclusive boutiques, galleries, restaurants and bars.

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Home in Santo Domingo de Guzman

A modern living area features two armchairs in rose color opposite a sleek marble coffee table. A television is mounted on the wall, and light filters through sheer curtains, illuminating the space. Decorative elements include a vase of flowers on the side table.

4.94 out of 5 average rating, 143 reviews

Cozy & Beautiful City Center House with Jacuzzi

The House is located in " El Cacique", one of the safest areas in the city, with access to Malecón ( Caribbean Sea), supermarket and clinics 5 minutes walk, access to Mirador Sur park, and 15-20 minutes from the most prestigious shopping centers in the city. Located approximately 40 minutes from the airport and 14 minutes from Zona Colonial.

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Home in Santo Domingo Este

4.95 out of 5 average rating, 111 reviews

Luxury house in the East Zone

Spacious luxury house with 2 levels, ideal for being with a partner, friends or family. It has all the necessary amenities for a pleasant and luxurious stay. Located in the eastern area, 15 minutes from Las Américas Airport. 2 minutes from Bravo Avenida Hípica and 5 minutes from Avenida Ecológica.

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An inviting rooftop terrace features a hanging chair and comfortable cushioned seating. A wooden coffee table stands at the center. Lush greenery provides a natural backdrop with trees visible, and the sky showcases soft clouds, creating a serene outdoor atmosphere.