
Guesthouse vacation rentals in Santo Domingo
Find and book unique guesthouse rentals on Airbnb
Quick stats about guesthouse rentals in Santo Domingo

Total vacation rentals
Explore 70 vacation rentals in Santo Domingo

Nightly prices starting at
Santo Domingo vacation rentals start at $10 per night before taxes and fees

Verified guest reviews
Over 1,710 verified reviews to help you choose

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
70 of Santo Domingo vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santo Domingo rentals
Top-rated guesthouse rentals in Santo Domingo
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Centric & Elegant Studio/Colonial Style/Ample Yard
Unique studio within a renovated property. Large patio with fence and electric gate. Ideally located, 2 miles away from the Colonial Zone, 3 from Downtown. Hospital, Laundry, Sea View within 2 blocks. Supermarket, restaurants, museums within 1 mile. Less than 0.5 miles away from 2 subway stations. Fast Wifi (100+ Mbps). Smart speaker can control lights, AC, adjust temperature or play your favorite music. 4K TV w/swivel base, includes YouTube, Netflix, PrimeVideo, Disney and Star+. Queen bed.

Private Cozy Apartment Studio
One bedroom studio, centrally located in the heart of El Millón, Santo Domingo, where comfort, convenience, and warm space offers the intimate feel of a family home, featuring: A private entrance for your complete privacy. Dedicated parking for your convenience and peace of mind. Whether you're visiting for leisure or business, our studio is thoughtfully designed to meet your needs. Remote workers will appreciate the high-speed internet, ensuring uninterrupted connectivity throughout your stay.

Giuliela Boutique Stay – Entire Residence
A private sanctuary where history meets intention. This exclusive stay includes both Luna and Sole Suites within GIULIELA, a beautifully restored 1930s residence in Gazcue. While guests enjoy their own private accommodations, my family and I reside in the main house, allowing us to offer personalized local recommendations, and attentive hospitality. Curated design, timeless charm, and a touch of quiet luxury create an intimate experience that blends authentic local living with refined comfort.

VillaMella Oasis 2bedroom2bathroom Patio Hot Water
Welcome to your Oasis in Villa Mella. Relax in comfort and luxury with a second-floor-level, 2 queen beds, 2 private baths, and a fold-out sofa. Enjoy A/C, hot water, fast WIFI, and 3 Roku TVs with Netflix. Secure smart lock entry and 24/7 on-site staff that will ensure peace of mind. Just a 5-minute walk from the Gregorio Gilbert Metro station. Bring the whole family to this great place with lots of room for fun. Need a driver? We've got you covered. Let us melt your stress away! Book now!

Cozy 2 BR with BBQ
This 2 bedroom apartment with BBQ private area is truly bright and cozy . It takes 25 minutes to arrive from the airport. The spacious master bedroom has a queen size bed and the very bright single room have two twins bed. You have discount with our car rental services with airport pick-up. The neighborhood is very safe, is private with access control and very clean, there are many restaurants nearby many bars, gyms, movie theaters, shopping malls . The neighbours are lovely and quiet.

Nido del patio, 40 min to Bocachica beach 5 center
You will have the entire apartment just for you. Enjoy the tranquility that the area offers, an ideal place to rest and work, and a strategic point to travel to places of interest You are responsible for cleaning the accommodation during your stay. It is delivered clean. If you need it, you can request cleaning service at an additional charge. The patio is rarely shared. Usually, only you will enjoy the patio. The host is in charge of cleaning the patio area.

Cozy apartment for work / holidays.
Comfortable apartment, on second level, with private parking, ideal for holiday trips, congresses, jobs and others. Close to shopping centers, Recreational park, clinics, universities; 25 minutes from the colonial area. Located in downtown area of the city, in the urbanization El Millón del Distrito Nacional. Peaceful, residential place with access to the main roads of the city.

Guest House in the city/pool/USA Embassy
You no longer need to leave the city to feel in the mountains, this is an independent 1 bed 1 bath Guest House in a closed residence with a 10-meter pool shared with the Hosts. With a Coway potable water filter. Supermarkets, Cinema, Shops, and Hair Salon nearby. A few minutes from the center of Santo Domingo and 1.8 km from the American Embassy.

Your little corner of peace in SDO
Kick back and relax in this calm, stylish space. “Tu rinconcito de Paz” is an oasis in the middle of the city rush, take some fresh air in our outdoor Gazebo area, enjoy the privacy and security of our small but cozy house. Commercial centers as Carrefour and numerous restaurants are located at 8 minutes away from our spot.

Villas Na’ Keys
Descubre un refugio único donde el confort, la privacidad y la belleza se combinan para ofrecer una experiencia inolvidable. Nuestra villa ha sido cuidadosamente diseñada para brindar un ambiente acogedor y elegante, ideal tanto para escapadas relajantes como para momentos especiales con familiares y amigos.

Cozy Separate Room in Santo Domingo Colonial
Aparta - Estudio- Privado con Patio compartido. Cómodo - espacioso, próximo a la zona colonial, palacio presidencial, parque independencia, Malecon. Primera ciudad del continente americano. Zona más turística de Santo Domingo. Most tourist area of santo domingo! Great for sightseeing

Private oasis with pool in a quiet residential area
Private pool just for you. Independent attached house with large garden and terrace ideal to enjoy as a family. Located in a quiet and safe residential area, close to everything. Air-conditioned and comfortable spaces. Perfect for getaways, weekends and a break in the city.
Popular amenities for Santo Domingo guesthouse rentals
Family-friendly guest house rentals

Room in Zona Colonial + Private Bathroom + Kitchenette

save your pocket

Cozy, quiet, safe

Vintage-Modern 2floor GuestHouse

Private apartment

Stay at Pepa's

3 Private Room El Vergel

Twin Bed Room-King Room Zona Colonial
Guest house rentals with a patio

EstWise GuestHouse • Moon Room •

"A Great Place To Be"

Nochebuena Room at Akaiah Guest House.

The best option

Beautiful room in the Colonial area

Relax in this cozy villa

Double suite room in Aut Las Américas

Charming Shelter - Suite #5
Guest house rentals with a washer and dryer

INVERTERS

Brisa Oriental

Bedroom inside apartment

Family-friendly and comfortable

Villa el paraíso, Guerra

Luxury apartment in Santuario

Casa en Villa Marina, Los Ríos de Santo Domingo

Secure★DCGen★Full Kitchen★100+Mbs★Comfy Bed★W/D
When is the best time to visit Santo Domingo?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $26 | $27 | $24 | $26 | $26 | $22 | $26 | $29 | $35 | $29 | $28 | $27 |
| Avg. temp | 78°F | 78°F | 79°F | 80°F | 81°F | 82°F | 83°F | 83°F | 83°F | 82°F | 81°F | 79°F |
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- Playa Nueva Romana
- Ciudad Juan Bosch
- Malecón
- Metro Country Club
- Playa Guayacanes
- Blue Mall
- Playa Hemingway
- Downtown Center
- Megacentro
- Agora Mall
- Zona Colonial
- Teatro Nacional Eduardo Brito
- Bella Vista Mall
- Galería 360
- Dr. Rafael Ma. Moscoso National Botanical Garden
- Parque Iberoamerica
- Cathedral of Santa María la Menor
- Columbus Park
- The 3 Eyes National Park
- Columbus Lighthouse
- Casa De Teatro
- Playa Caribe
- Independence Park
- Kahkow Experience
- Things to do Santo Domingo
- Nature and outdoors Santo Domingo
- Food and drink Santo Domingo
- Things to do Distrito Nacional
- Nature and outdoors Distrito Nacional
- Art and culture Distrito Nacional
- Food and drink Distrito Nacional
- Things to do Dominican Republic
- Tours Dominican Republic
- Nature and outdoors Dominican Republic
- Sightseeing Dominican Republic
- Food and drink Dominican Republic
- Entertainment Dominican Republic
- Sports activities Dominican Republic
- Art and culture Dominican Republic
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
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- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes







